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  1. Regular use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been consistently associated with reduced risk of colorectal cancer and adenoma, and there is some evidence for a protective ...

    Authors: Ravi J Menezes, Kenneth R Huber, Martin C Mahoney and Kirsten B Moysich

    Citation: BMC Public Health 2002 2:18

    Content type: Research article

    Published on:

  2. Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the clinical stage of KS. To examine t...

    Authors: Abeltje M Polstra, J Goudsmit and M Cornelissen

    Citation: BMC Infectious Diseases 2002 2:18

    Content type: Research article

    Published on:

  3. All current UK indices of socio-economic status have inherent problems, especially those used to govern resource allocation to the health sphere. The search for improved markers continues: this study proposes ...

    Authors: Norman R Beale, Gordon J Taylor and Dawn MK Straker-Cook

    Citation: BMC Public Health 2002 2:17

    Content type: Hypothesis

    Published on:

  4. Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed for...

    Authors: Mark Loeb, Kevin Brazil, Lynne Lohfeld, Allison McGeer, Andrew Simor, Kurt Stevenson, Stephen Walter and Dick Zoutman

    Citation: BMC Health Services Research 2002 2:17

    Content type: Study protocol

    Published on:

  5. Tetracycline-regulated systems have been used to control the expression of heterologous genes in such diverse organisms as yeast, plants, flies and mice. Adaptation of this prokaryotic regulatory system avoids...

    Authors: Paraic A Kenny, Tariq Enver and Alan Ashworth

    Citation: BMC Molecular Biology 2002 3:13

    Content type: Methodology article

    Published on:

  6. Anandamide (N-arachidonoylethanolamine, AEA) belongs to an emerging class of endogenous lipids, called "endocannabinoids". A specific AEA membrane transporter (AMT) allows the import of this lipid and its degrada...

    Authors: Natalia Battista, Monica Bari, Alessandro Finazzi-Agrò and Mauro Maccarrone

    Citation: Lipids in Health and Disease 2002 1:1

    Content type: Short paper

    Published on:

  7. The mechanism by which Bacillus anthracis initiates anthrax in humans involves key protein-protein interactions, the site for which have now been mapped

    Authors: Wim D'Haeze

    Citation: Genome Biology 2002 3:reports0051

    Content type: Paper report

    Published on:

  8. Understanding the secretion of an enterotoxin by enterotoxigenic Escherichia coli strains paves the way to the development of new drugs

    Authors: Wim D'Haeze

    Citation: Genome Biology 2002 3:reports0049

    Content type: Paper report

    Published on:

  9. Sequencing Thermoanaerobacter tengcongensis reveals clues as to how this thermophile manages to live an extreme lifestyle

    Authors: Wim D'Haeze

    Citation: Genome Biology 2002 3:reports0048

    Content type: Paper report

    Published on:

  10. The specificity of tissue transcriptional activities may be understood via high-throughput gene-expression profiling of a significant fraction of the human and mouse transcriptomes

    Authors: Chris Berrie

    Citation: Genome Biology 2002 3:reports0047

    Content type: Paper report

    Published on:

  11. Drugs & used in anticancer chemotherapy have severe effects upon the cellular transcription and replication machinery. From in vitro studies it has become clear that these drugs can affect specific genes, as well...

    Authors: Antoinette C van der Kuyl, Remco van den Burg, Fokla Zorgdrager, John T Dekker, Jolanda Maas, Carel JM van Noesel, Jaap Goudsmit and Marion Cornelissen

    Citation: BMC Cancer 2002 2:21

    Content type: Research article

    Published on:

  12. The C1D gene is expressed in a broad spectrum of mammalian cells and tissues but its product induces apoptotic cell death when exceeding a critical level. Critical levels are achieved in a fraction of cells by...

    Authors: Karsten Rothbarth, Hermann Stammer and Dieter Werner

    Citation: Cancer Cell International 2002 2:12

    Content type: Primary research

    Published on:

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