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  1. Baicalein is a widely used Chinese herbal medicine derived from Scutellaria baicalenesis, which has been traditionally used as anti-inflammatory and anti-cancer therapy. In this study we examined the anti-tumour ...

    Authors: Mary-Clare Cathcart, Zivile Useckaite, Clive Drakeford, Vikki Semik, Joanne Lysaght, Kathy Gately, Kenneth J. O’Byrne and Graham P. Pidgeon

    Citation: BMC Cancer 2016 16:707

    Content type: Research article

    Published on:

  2. Although cis-diamminedichloro-platinum (CDDP) exhibits strong therapeutic effects in cancer chemotherapy, its adverse effects such as peripheral neuropathy, nephropathy, and vomiting are dose-limiting factors. Pr...

    Authors: Yoshihiro Seto, Fumiyasu Okazaki, Keiji Horikawa, Jing Zhang, Hitoshi Sasaki and Hideto To

    Citation: BMC Cancer 2016 16:756

    Content type: Research article

    Published on:

  3. Cancer patients are predominantly treated as out-patients and as they often experience difficult symptoms and side effects it is important to facilitate and improve patient-clinician communication to support s...

    Authors: Ann Langius-Eklöf, Marie-Therése Crafoord, Mats Christiansen, Maria Fjell and Kay Sundberg

    Citation: BMC Cancer 2017 17:466

    Content type: Study protocol

    Published on:

  5. Base excision repair (BER) pathway is a DNA repair pathway that is important in carcinogenesis and in response to DNA-damaging chemotherapy. XRCC1 is one of important molecular markers for BER. So far, the rol...

    Authors: Dan-Juan Li and Dong Xiao

    Citation: BMC Cancer 2017 17:501

    Content type: Research article

    Published on:

  6. Breast cancer is currently the most common neoplasm diagnosed in women globally. There is a growing body of evidence to suggest that human papillomavirus (HPV) infection may play a key role in invasiveness of ...

    Authors: Niloofar Khodabandehlou, Shayan Mostafaei, Ashkan Etemadi, Amir Ghasemi, Mehrdad Payandeh, Shima Hadifar, Amir Hossein Norooznezhad, Anoshirvan Kazemnejad and Mohsen Moghoofei

    Citation: BMC Cancer 2019 19:61

    Content type: Research article

    Published on:

  7. To explore the patterns of failures and areas at highest risk of recurrence for postoperative intrahepatic cholangiocarcinoma (IHCC), with the aim to guide IHCC adjuvant radiotherapy.

    Authors: Wei Yu, Chunxiu Hu, Yongjie Shui, Kui Wu, Lili Zhang, Ying Chen, Chao Li, Jing Xu and Qichun Wei

    Citation: BMC Cancer 2019 19:1108

    Content type: Research article

    Published on:

  8. Several randomized controlled trials have shown that adjuvant immunotherapy with autologous cytokine-induced killer (CIK) cells prolongs recurrence-free survival (RFS) after curative treatment for hepatocellul...

    Authors: Jun Sik Yoon, Byeong Geun Song, Jeong-Hoon Lee, Hyo Young Lee, Sun Woong Kim, Young Chang, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Dong Hyun Sinn, Yoon Jun Kim, Joon Hyeok Lee and Jung-Hwan Yoon

    Citation: BMC Cancer 2019 19:523

    Content type: Research article

    Published on:

  9. Outcomes of patients with ovarian high-grade serous carcinoma (HGSC) treated with neoadjuvant chemotherapy (NAC) have been widely studied, but there is limited information on the outcomes of patients with non-...

    Authors: Young Shin Chung, Sang-Yoon Park, Jung-Yun Lee, Jeong-Yeol Park, Jeong-Won Lee, Hee Seung Kim, Dong Soo Suh, Yun Hwan Kim, Jong-Min Lee, Miseon Kim, Min Chul Choi, Seung-Hyuk Shim, Keun Ho Lee, Taejong Song, Jin Hwa Hong, Won Moo Lee…

    Citation: BMC Cancer 2019 19:341

    Content type: Research article

    Published on:

  10. Factors beyond the individual level such as those characterizing the residential environment may be important to breast cancer outcomes. We provide a systematic review and results of meta-analysis of the publi...

    Authors: Tomi F Akinyemiju, Jeanine M Genkinger, Maggie Farhat, Adrienne Wilson, Tiffany L Gary-Webb and Parisa Tehranifar

    Citation: BMC Cancer 2015 15:191

    Content type: Research article

    Published on:

  11. We wished to evaluate the efficacy and safety of liposomal paclitaxel and docetaxel for induction chemotherapy (IC) for nasopharyngeal carcinoma (NPC).

    Authors: Sai-Lan Liu, Xue-Song Sun, Xiao-Yun Li, Qiu-Yan Chen, Huan-Xin Lin, Yue-Feng Wen, Shan-Shan Guo, Li-Ting Liu, Hao-Jun Xie, Qing-Nan Tang, Yu-Jing Liang, Jin-Jie Yan, Chao Lin, Zhen-Chong Yang, Lin-Quan Tang, Ling Guo…

    Citation: BMC Cancer 2018 18:1279

    Content type: Research article

    Published on:

  12. Circulating cell-free DNA (cfDNA) is emerging as a surrogate sample type for mutation analyses. To improve the clinical utility of cfDNA, we developed a sensitive peptide nucleic acid (PNA)-based method for an...

    Authors: Ji-Youn Han, Jae-Jin Choi, Jin Young Kim, You Lim Han and Geon Kook Lee

    Citation: BMC Cancer 2016 16:627

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cancer 2016 16:803

  13. There is increasing evidence supporting the concept of cancer stem cells (CSCs), which are responsible for the initiation, growth and metastasis of tumors. CSCs are thus considered the target for future cancer...

    Authors: Wenyi Gu, Indira Prasadam, Meihua Yu, Fengxia Zhang, Patrick Ling, Yin Xiao and Chengzhong Yu

    Citation: BMC Cancer 2015 15:609

    Content type: Research article

    Published on:

  14. In recent years management practices in relation to low-risk papillary microcarcinoma (PMC) have been evolving with increased awareness of the potential overdiagnosis and overtreatment of PMCs, and guidelines ...

    Authors: Brooke Nickel, Juan P. Brito, Ray Moynihan, Alexandra Barratt, Susan Jordan and Kirsten McCaffery

    Citation: BMC Cancer 2018 18:242

    Content type: Research article

    Published on:

  15. No study has been conducted to investigate the spatial pattern and association of socioeconomic status (such as income) with breast and colorectal cancer incidence in Texas, United States. This study aimed to ...

    Authors: Zheyu Liu, Kai Zhang and Xianglin L. Du

    Citation: BMC Cancer 2016 16:294

    Content type: Research article

    Published on:

  16. Antiangiogenic therapies are considered promising for the treatment of glioblastoma (GB). The non-collagenous C-terminal globular NC1 domain of type VIII collagen a1 chain, Vastatin, is an endogenous antiangio...

    Authors: Yi Li, Jun Li, Yat Ming Woo, Zan Shen, Hong Yao, Yijun Cai, Marie Chia-mi Lin and Wai Sang Poon

    Citation: BMC Cancer 2017 17:126

    Content type: Research article

    Published on:

  18. Hepatoma-derived growth factor (HDGF) participates in angiogenesis and represents a negative prognostic factor in oral cancer. The current study was designed to elucidate the regulatory mechanism between HDGF ...

    Authors: Yu-Wei Lin, Shih-Tsung Huang, Jian-Ching Wu, Tian-Huei Chu, Shih-Chung Huang, Ching-Chih Lee and Ming-Hong Tai

    Citation: BMC Cancer 2019 19:1083

    Content type: Research article

    Published on:

  19. Neuroblastoma (NB) is a frequent pediatric tumor characterized by a poor prognosis where a majority of tumors progress despite intensive multimodality treatments. Autophagy, a self-degradative process in cells...

    Authors: Assila Belounis, Carine Nyalendo, Roxane Le Gall, Tina V. Imbriglio, Mohamed Mahma, Pierre Teira, Mona Beaunoyer, Sonia Cournoyer, Elie Haddad, Gilles Vassal and Hervé Sartelet

    Citation: BMC Cancer 2016 16:891

    Content type: Research article

    Published on:

  20. Colorectal cancer is the third most common cancer worldwide; and in 40% of all cases, KRAS4b-activating mutations occur. KRAS4b is transported by phosphodiesterase-6δ (PDEδ) to the plasma membrane, where it ge...

    Authors: Pedro Cruz-Nova, Michael Schnoor, José Correa-Basurto, Martiniano Bello, Paola Briseño-Diaz, Arturo Rojo-Domínguez, Carlos M. Ortiz-Mendoza, Jorge Guerrero-Aguirre, Francisco J. García-Vázquez, Rosaura Hernández-Rivas, María del Rocío Thompson-Bonilla and Miguel Vargas

    Citation: BMC Cancer 2018 18:1056

    Content type: Research article

    Published on:

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