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  2. Beneficial effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) against recurrent colorectal adenomas have been documented in systematic reviews; however, the results have not been ...

    Authors: Sajesh K. Veettil, Kean Ghee Lim, Siew Mooi Ching, Surasak Saokaew, Pochamana Phisalprapa and Nathorn Chaiyakunapruk

    Citation: BMC Cancer 2017 17:763

    Content type: Research article

    Published on:

  3. Colorectal cancer is the third most common malignancy in humans and novel therapeutic approaches are urgently needed. Autophagy is an evolutionarily highly conserved cellular process by which cells collect unn...

    Authors: Bruno Christian Koehler, Adam Jassowicz, Anna-Lena Scherr, Stephan Lorenz, Praveen Radhakrishnan, Nicole Kautz, Christin Elssner, Johanna Weiss, Dirk Jaeger, Martin Schneider and Henning Schulze-Bergkamen

    Citation: BMC Cancer 2015 15:919

    Content type: Research article

    Published on:

  4. Pulmonary imaging often identifies suspicious abnormalities resulting in supplementary diagnostic procedures. This study aims to investigate whether the metabolic fingerprint of plasma allows to discriminate b...

    Authors: K. Vanhove, P. Giesen, O. E. Owokotomo, L. Mesotten, E. Louis, Z. Shkedy, M. Thomeer and P. Adriaensens

    Citation: BMC Cancer 2018 18:868

    Content type: Research article

    Published on:

  5. Though the management of malignancies has improved vastly in recent years, many treatment options lack the desired efficacy and fail to adequately augment patient morbidity and mortality. It is increasingly cl...

    Authors: Andrew Riley, Victoria Green, Ramsah Cheah, Gordon McKenzie, Laszlo Karsai, James England and John Greenman

    Citation: BMC Cancer 2019 19:259

    Content type: Research article

    Published on:

  6. Associations between polymorphisms of UDP-glucuronosyltransferases (UGTs) or efflux transporters (e.g., P-glycoprotein and MRP2) and different types of cancer have been described, whereas the role of influx tr...

    Authors: Sabrina Falkowski, Jean-Baptiste Woillard, Deborah Postil, Nicole Tubiana-Mathieu, Eric Terrebonne, Antoine Pariente, Denis Smith, Rosine Guimbaud, Claire Thalamas, Koukeb Rouguieg-Malki, Pierre Marquet and Nicolas Picard

    Citation: BMC Cancer 2017 17:901

    Content type: Research article

    Published on:

  7. Cancer cells exhibit increased glycolysis for ATP production (the Warburg effect) and macromolecular biosynthesis; it is also linked with therapeutic resistance that is generally associated with compromised re...

    Authors: Anant Narayan Bhatt, Ankit Chauhan, Suchit Khanna, Yogesh Rai, Saurabh Singh, Ravi Soni, Namita Kalra and Bilikere S Dwarakanath

    Citation: BMC Cancer 2015 15:335

    Content type: Research article

    Published on:

  8. Distant metastasis resulting from vascular dissemination of cancer cells is the primary cause of mortality from breast cancer. We have previously reported that E-selectin expression on the endothelial cell sur...

    Authors: Shin-Ae Kang, Celine A. Blache, Sandra Bajana, Nafis Hasan, Mohamed Kamal, Yoshihiro Morita, Vineet Gupta, Bilegtsaikhan Tsolmon, K. Stephen Suh, David G. Gorenstein, Wajeeha Razaq, Hallgeir Rui and Takemi Tanaka

    Citation: BMC Cancer 2016 16:331

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cancer 2016 16:370

  9. Tumor angiogenesis is vital for tumor growth. Recent evidence indicated that bone marrow-derived mesenchymal stem cells (BMSCs) can migrate to tumor sites and exert critical effects on tumor growth through dir...

    Authors: Chao Sun, Xingliang Dai, Dongliang Zhao, Haiyang Wang, Xiaoci Rong, Qiang Huang and Qing Lan

    Citation: BMC Cancer 2019 19:1240

    Content type: Research article

    Published on:

  10. Hepatocyte carcinoma (HCC) is one of the most common malignancies worldwide. Despite many achievements in diagnosis and treatment, HCC mortality remains high due to the malignant nature of the disease. Novel a...

    Authors: Hao Liu, Qun Wei, Jia Wang, Xiaoming Huang, Chunchun Li, Qiaoli Zheng, Jiang Cao and Zhenyu Jia

    Citation: BMC Cancer 2015 15:325

    Content type: Research article

    Published on:

  11. Carbonic anhydrase IX (CA IX) is a tumor-associated, highly active, transmembrane carbonic anhydrase isoform regulated by hypoxia and implicated in pH control and adhesion-migration-invasion. CA IX ectodomain ...

    Authors: Ivana Vidlickova, Franck Dequiedt, Lenka Jelenska, Olga Sedlakova, Michal Pastorek, Stanislav Stuchlik, Jaromir Pastorek, Miriam Zatovicova and Silvia Pastorekova

    Citation: BMC Cancer 2016 16:239

    Content type: Research article

    Published on:

  12. Many cancers are preventable through lifestyle modification; however, few adults engage in behaviors that are in line with cancer prevention guidelines. This may be partly due to the mixed messages on effectiv...

    Authors: Sarah E. Neil-Sztramko, Emily Belita, Anthony J. Levinson, Jennifer Boyko and Maureen Dobbins

    Citation: BMC Cancer 2019 19:1138

    Content type: Research article

    Published on:

  13. Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant brain tumors with inactivation of the SMARCB1 gene, which play a critical role in genomic transcriptional control. In this study, we analyzed the ge...

    Authors: Ji Hoon Phi, Choong-Hyun Sun, Se-Hoon Lee, Seungmook Lee, Inho Park, Seung Ah Choi, Sung-Hye Park, Ji Yeoun Lee, Kyu-Chang Wang, Seung-Ki Kim, Hongseok Yun and Chul-Kee Park

    Citation: BMC Cancer 2019 19:848

    Content type: Research article

    Published on:

  14. In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of ge...

    Authors: Lenka Kalinkova, Iveta Zmetakova, Bozena Smolkova, Gabriel Minarik, Tatiana Sedlackova, Viera Horvathova Kajabova, Zuzana Cierna, Michal Mego and Ivana Fridrichova

    Citation: BMC Cancer 2018 18:875

    Content type: Research article

    Published on:

  15. With the introduction of Olaparib treatment for BRCA-deficient recurrent ovarian cancer, testing for somatic and/or germline mutations in BRCA1/2 genes in tumor tissues became essential for treatment decisions. I...

    Authors: Falk Zakrzewski, Laura Gieldon, Andreas Rump, Michael Seifert, Konrad Grützmann, Alexander Krüger, Sina Loos, Silke Zeugner, Karl Hackmann, Joseph Porrmann, Johannes Wagner, Karin Kast, Pauline Wimberger, Gustavo Baretton, Evelin Schröck, Daniela Aust…

    Citation: BMC Cancer 2019 19:396

    Content type: Technical advance

    Published on:

  16. The optimal therapeutic strategy in UICC stage T3 hepatocellular carcinoma (HCC) patients that maximizes both safety and long-term outcome has not yet been determined. Our aim was to compare clinical outcomes ...

    Authors: Chong Zhong, Yong-Fa Zhang, Jun-Hai Huang, Cheng-Ming Xiong, Zi-Yu Wang, Qing-Lian Chen and Rong-Ping Guo

    Citation: BMC Cancer 2018 18:643

    Content type: Research article

    Published on:

  17. To date, standardized strategies for the treatment of recurrent glioma are lacking. Chemotherapy with the alkylating agent BCNU (1,3-bis (2-chloroethyl)-1-nitroso-urea) is a therapeutic option even though its ...

    Authors: Christine Jungk, Despina Chatziaslanidou, Rezvan Ahmadi, David Capper, Justo Lorenzo Bermejo, Janina Exner, Andreas von Deimling, Christel Herold-Mende and Andreas Unterberg

    Citation: BMC Cancer 2016 16:81

    Content type: Research article

    Published on:

  18. The ras genes play an important role in the development and progression of human tumours. Neutralizing Ras proteins in the cytoplasm could be an effective approach to blocking ras signalling. In this study, we pr...

    Authors: Ju-Lun Yang, Du-Xian Liu, Shi-Jian Zhen, Yun-Gang Zhou, Dai-Jun Zhang, Li-Ying Yang, Hao-Bing Chen and Qiang Feng

    Citation: BMC Cancer 2016 16:131

    Content type: Research article

    Published on:

  19. The VeriStrat test is a serum proteomic signature originally discovered in non-responders to second line gefitinib treatment and subsequently used to predict differential benefit from erlotinib versus chemothe...

    Authors: Mary Jo Fidler, Cristina L. Fhied, Joanna Roder, Sanjib Basu, Selina Sayidine, Ibtihaj Fughhi, Mark Pool, Marta Batus, Philip Bonomi and Jeffrey A. Borgia

    Citation: BMC Cancer 2018 18:310

    Content type: Research article

    Published on:

  20. Androgens, through their own receptor, play a protective role on breast tumor development and progression and counterbalance estrogen-dependent growth stimuli which are intimately linked to breast carcinogenesis.

    Authors: Francesca De Amicis, Chiara Chiodo, Catia Morelli, Ivan Casaburi, Stefania Marsico, Rosalinda Bruno, Diego Sisci, Sebastiano Andò and Marilena Lanzino

    Citation: BMC Cancer 2019 19:1038

    Content type: Research article

    Published on:

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